Xarelto® is a blood thinner that treats or prevents blood clots. You may need it if you had a blood clot in your leg or lung. Or you may need it because you have atrial fibrillation but no heart valve issues. Xarelto also prevents clots after surgery to replace your knee or hip.

Xarelto was invented in Bayer's Wuppertal laboratories in Germany, and is being jointly developed by Bayer HealthCare and Johnson & Johnson Pharmaceutical Research & Development, L.L.C. The Bayer Group is a global enterprise with core competencies in the fields of health care, nutrition and high-tech materials.

XARELTO® is licensed from Bayer HealthCare AG, 51368 Leverkusen, Germany. Get additional support from Janssen CarePath to help you start and stay on therapy, visit JanssenCarePath.com,or call us.

High-Alert Medicines Xarelto is a high-alert medicine. This means that Xarelto has been proven to be safe and effective, but serious harm, such as severe bleeding or a stroke, can occur if it is not taken exactly as directed.

Eating grapefruit or drinking grapefruit juice while taking Xarelto could raise the level of the medication in your body. A higher level of Xarelto could increase your risk of side effects from the drug. Your doctor may advise you to avoid eating grapefruit or drinking grapefruit juice during Xarelto treatment.

Xarelto (rivaroxaban) is a medication used to treat and prevent blood clots. The most common side effect of Xarelto is unwanted bleeding. Other side effects include stomach pain, back pain, and itchy skin. Bleeding from Xarelto can be mild or severe.

Xarelto is only available as a brand-name drug. It doesn't come in a generic version. A generic drug is an exact copy of the active drug in a brand-name medication. Generics tend to cost less than brand-name drugs.

Xarelto, also known as rivaroxaban, is sold in the United States by Johnson & Johnson (JNJ. N) arm Janssen Pharmaceuticals. Eliquis, also known as apixaban, was co-developed by Pfizer Inc (PFE. N) and Bristol Myers Squibb (BMY.

History of Xarelto Xarelto was first approved for marketing authorization in Canada in September 2008 to prevent venous thromboembolism (VTE) in people who have undergone elective total hip replacement or total knee replacement surgery.

So it's not unusual that the drug increases your risk for bleeding. But it's important to be aware that Xarelto can cause bleeding anywhere in your body, including internal bleeding. Internal bleeding can affect your organs, such as your stomach, lungs, brain, and eyes. Xarelto may cause both mild and severe bleeding.

The typical dosage of Xarelto after hip replacement is 10 mg per day for 35 days. And, the typical dosage after knee replacement is 10 mg per day for 12 days. For these uses, you can take Xarelto with or without food.