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What is Movantik?
Movantik: Overview and Uses
Movantik is a medication used to treat opioid-induced constipation (OIC) in adults with chronic non-cancer pain. It is a prescription-only medication containing the active ingredient naloxegol oxalate, which works by blocking the effects of opioids on the bowel.
How does Movantik work?
Opioids are pain-relieving drugs that work by binding to specific receptors in the brain and body. However, opioids can also bind to receptors in the gut, which can slow down bowel movements and lead to constipation. As a peripherally-acting mu-opioid receptor antagonist, Movantik selectively blocks the mu-opioid receptors in the gut, restoring bowel movements in patients with OIC.
Dosage and Administration of Movantik
Movantik is available in the form of a tablet and should be taken once a day on an empty stomach, at least an hour before the first meal of the day or two hours after it. The recommended dosage is 25 milligrams (mg) once a day, which may be decreased to 12.5 mg once daily in certain patients. It is important to follow the dosage instructions provided by the healthcare provider.
Side Effects of Movantik
Common side effects associated with Movantik include stomach pain, diarrhea, nausea, flatulence, vomiting, and headaches. In rare cases, Movantik may cause serious side effects, such as severe allergic reactions, perforation or obstruction in the bowel, and opioid withdrawal symptoms.
Precautions and Interactions
Movantik should not be used in patients with a known or suspected bowel obstruction or a history of bowel perforation. It may also interact with certain medications, such as strong CYP3A4 inhibitors and inducers, and should not be used concomitantly with some medications. Patients should inform their healthcare providers about all medications and supplements they are taking.
In conclusion, Movantik is a medication used to treat opioid-induced constipation in adults with chronic non-cancer pain. It works by selectively blocking the mu-opioid receptors in the gut, restoring bowel movements. Movantik is available in the form of a tablet and should be taken once a day on an empty stomach, at least an hour before the first meal of the day or two hours after it. Patients are advised to follow the dosage instructions provided by their healthcare providers and report any side effects or possible interactions.
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Movantik
What is Movantik?Movantik is a medication used to treat opioid-induced constipation (OIC) in adults with chronic non-cancer pain , including chronic pain related to prior cancer or its treatment. It i...
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