MOVANTIK blocks opioids from attaching to something called “mu-receptors” in your bowels - directly targeting the area impacted by opioid-induced constipation. This design helps provide relief efficiently and enable bowel movements.

If Movantik (naloxegol) doesn't work well enough, you can continue to take laxatives like Dulcolax (bisacodyl) or enemas to help with your constipation. Is Movantik (naloxegol) a stool softener?

MOVANTIK is a prescription medicine used to treat constipation that is caused by prescription pain medicines called opioids, in adults with long-lasting (chronic) pain that is not caused by active cancer.

You should also stop taking other laxatives before you start treatment with MOVANTIK.

Movantik reduces constipation caused by opioid pain medicine used to treat severe chronic pain. It works by treating constipation without reducing the pain-relieving effects of the opioid.

Brand Name: Movantik Generic Name: Naloxegol Manufacturer3: AstraZeneca Drug Class1,2: Peripherally Acting Mu Opioid Receptor Antagonist (PAMORA) Labeled Uses1,2,3,4. Opioid-induced constipation, Chronic non-cancer pain Mechanism of Action:1,2,3,4.

Eat a high-fiber diet. Fiber adds bulk to stool and helps the stool hold fluids. These factors give stool the right shape and weight to move through the colon. Fiber-rich foods include fruits, vegetables, beans, and whole-grain bread, cereal and rice. Increase dietary fiber slowly to prevent bloating and gas.

In 2 clinical studies, MOVANTIK worked quickly - often within 6 to 12 hours of the first dose. MOVANTIK is taken once a day in the morning, on an empty stomach,* for the duration of opioid treatment. In the same 2 studies, response rate for MOVANTIK was 40% to 44% with a 25 mg dose and 35% to 41% with a 12.5 mg dose.

Take this medication by mouth on an empty stomach at least 1 hour before or 2 hours after a meal, as directed by your doctor, usually once daily in the morning. If you are unable to swallow this medication whole, you may crush the tablets to a powder, mix in 4 ounces (120 milliliters) of water and drink immediately.

osmotic laxatives – such as lactulose and polyethylene glycol, which soften your stools and make them easier to pass by increasing the amount of water in your bowels.

An example of a stool softener is docusate (1 brand name: Colace). These cause the intestine to hold more fluid. This softens stools and helps the bowel move them out. Examples include polyethylene glycol (1 brand name: Miralax) and magnesium hydroxide solution (brand name: Milk of Magnesia).

MOVANTIK is taken once a day in the morning, on an empty stomach,* for the duration of opioid treatment.