OSPHENA (ospemifene) is indicated for: The treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. The treatment of moderate to severe vaginal dryness, a symptom of vulvar and vaginal atrophy, due to menopause.

There doesn't seem to be a higher risk of endometrial cancer if you take Osphena for less than 1 year. But the risk goes up significantly the longer you take it. Studies have shown a higher risk of stroke within the first year of treatment and a higher risk of blood clots within the first 2 years of treatment.

Who should not take OSPHENA? Osphena should not be used if you have unusual vaginal bleeding, have or have had certain types of cancers, have or have had blood clots, had a stroke or heart attack, have severe liver problems, are allergic to Osphena or any of its ingredients, or think you may be pregnant.

Each OSPHENA tablet contains 60 mg of ospemifene. Inactive ingredients include colloidal silicon dioxide, hypromellose, lactose monohydrate, magnesium stearate, mannitol, microcrystalline cellulose, polyethylene glycol, povidone, pregelatinized starch, sodium starch glycolate, titanium dioxide, and triacetin.

How to use Osphena. Read the Patient Information Leaflet if available from your pharmacist before you start taking ospemifene and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with food as directed by your doctor, usually once daily.

Some women develop this problem right after childbirth or while breastfeeding. Estrogen levels are lower at these times. The vagina can also become further irritated from soaps, laundry detergents, lotions, perfumes, or douches. Certain medicines, smoking, tampons, and condoms may also cause or worsen vaginal dryness.

The cost for Osphena oral tablet 60 mg is around $780 for a supply of 90 tablets, depending on the pharmacy you visit.

Vitamins A, B, and E, as well as supplements like vaginal DHEA, can help increase lubrication.

Ospemifene oral tablets. Ospemifene treats vaginal dryness and painful sexual intercourse caused by menopause. This is a natural part of aging and marks the end of your reproductive years. Ospemifene comes in a tablet form that you can take by mouth with a glass of water as directed.

How soon can I expect results with Osphena®? In clinical studies, most women reported relief of moderate to severe vaginal dryness and/or moderate to severe painful sex due to menopause in as little as 12 weeks after beginning treatment with Osphena®.

You can still have the risk of uterine cancer several years after stopping Osphena (ospemifene). A warning symptom of uterine (endometrial) cancer includes vaginal bleeding that doesn't go away or keeps coming back.

How Long Does Vaginal Dryness Last? If your vaginal dryness is caused by non-estrogen-related factors, your vagina should return to a normal, healthy state shortly after you've identified and stopped the behavior that may be causing the dryness.

OSPHENA is an estrogen agonist/antagonist with tissue selective effects. In the endometrium, OSPHENA has agonistic effects. An increased risk of endometrial cancer has been reported with the use of unopposed estrogen therapy in a woman with a uterus.