This medicine is used for heartburn and acid reflux, indigestion, diarrhoea and feeling sick (nausea). It works by protecting your stomach and the lower part of your food pipe from stomach acid. It is also a mild antacid, which helps reduce too much stomach acid and eases any discomfort.

The medicine forms a protective coating over the lower part of your food pipe (oesophagus), and partly coats your stomach. This helps protect them from stomach acid. It also has weak antacid properties that may help reduce too much stomach acid. This will ease feelings of pain and discomfort.

Mechanism of Action The antidiarrheal effect of BSS is most likely due to: The reduction in prostaglandin formation, as BSS inhibits cyclooxygenase. Prostaglandin induces inflammation and hypermotility. The stimulation of reabsorption of fluids, sodium, and chloride - this action helps decrease fluid loss.

For diarrhea or upset stomach: Adults and teenagers - The usual dose is 2 tablets every half-hour to one hour. You should not take more than 16 tablets in twenty-four hours.

For many people, Pepto-Bismol is a safe, easy way to relieve common stomach problems. But if you have any concerns about whether Pepto-Bismol is a safe option for you, be sure to ask your doctor or pharmacist. Also call your doctor if Pepto-Bismol doesn't ease your symptoms after 2 days.

Sometimes referred to as "the pink stuff," Pepto-Bismol is an over-the-counter (OTC) medication that is safe and effective for short-term use. Side effects are generally mild and can include a black tongue, black stool, and constipation. More serious side effects can occur but are rare.

In Each Tablet: Active Ingredients: Bismuth Subsalicylate (262 Mg), Upset Stomach Reliever And Antidiarrheal. Inactive Ingredients: Calcium Carbonate, D&C Red No. 27 Aluminun Lake, Flavor, Magnesium Stearate, Mannitol, Povidone, Saccharin Sodium, Talc.

*Pepto is the #1 Pharmacist recommended brand based on a Pharmacy Times 2022 Survey-upset stomach remedies category.

Where does the name come from? Pepto was a marketeer's version of pepsin, a natural substance that aids digestion. Bismol is named for bismuth, the active ingredient that works, Schwartz says, by “coating the stomach.” Even though Pepto is now pepsin-less, no one could bear to change the name.

Taking too much Pepto-Bismol can increase the risk of side effects, including feeling or being sick, feeling confused, dizzy or tired, deafness, or ringing or buzzing in your ears.

The Pepto Bismol website recommends taking:

1. One 30 ml dose every 30 minutes as needed for stomach upset, nausea, heartburn, and indigestion.
2. One 30 ml dose every 30 minutes or two doses every hour for diarrhea or traveler's diarrhea.

Avoid Pepto Bismol if you take aspirin regularly. It is not advisable during pregnancy and breastfeeding. Children under 12 years of age should not take salicylate products due to an increased risk for Reye's Syndrome.