Estradiol topical gel and spray are used to treat and prevent hot flushes (hot flashes; sudden strong feelings of heat and sweating) in women who are experiencing menopause (change of life; the end of monthly menstrual periods).

How does your body make estriol? Your developing baby's adrenal glands make a hormone (a type of chemical) called dehydroepiandrosterone sulfate (DHEAS). The baby's liver changes this hormone into another chemical called 16a-hydroxy-DHEAS. This chemical travels to the placenta, where it changes into estriol.

EstroGel® 0.06% is approved by the FDA for use after menopause to reduce moderate to severe hot flashes and to treat moderate to severe menopausal changes in and around the vagina.

Epidermal thinning is associated with aging, and topical estradiol has been shown to reduce epidermal thinning in aging skin and maintain skin thickness (Shah and Maibach 2001).

Using this medicine over a long period of time may increase your risk of breast cancer, endometrial cancer, or uterine cancer. Talk with your doctor about this risk. If you still have your uterus (womb), ask your doctor if you should also use a progestin medicine.

YES. Even if you're not a candidate for MHT, you can use estriol face cream. Studies have confirmed that like local, topical vaginal estradiol, topical facial estriol does not increase systemic serum levels of estrogen. There are no hormonal side effects.

Research has shown that topical estriol can help maintain skin health by increasing collagen production, retaining and restoring skin moisture, increasing skin firmness and elasticity, and decreasing pore size and wrinkle depth.

It usually takes a few weeks before you feel the benefits of HRT. It can take up to 3 months to feel the full effects. If you have not felt the benefit of HRT after 4 to 6 months, it may help to try a different type. It can take your body time to get used to HRT.

It is advisable to put the estrogen gel or spray on after having a shower if this is not possible, try to leave as much time as you can between applying the gel or spray and taking a shower, bath or going swimming.

The estrogen darkens skin. Progesterone lightens it. The process works just as well on cells from men's skin as women's skin. “This is going to be a big deal in dermatology,” said Thomas Leung, another dermatologist at Penn.

Estrogen reaches it peak at this stage, right before ovulation, which means your skin is going to look its most healthy and glowing! No need to overdo it with products or treatments during this stage.

Estrogen is the most commonly used hormone in fertility therapy. In actuality, estrogen is three different hormones in the body: estradiol, estrone, and estriol. Estradiol is prescribed for some types of infertility and other women's health conditions.

Using this medicine may increase your risk of dementia, especially in women 65 years of age and older. Using this medicine may increase your risk for having blood clots, strokes, or heart attacks. This risk may continue even after you stop using the medicine.