comedian Larry the Cable Guy The marketing campaign will continue to feature comedian Larry the Cable Guy, who has acted as a Prilosec OTC spokesperson since last year.

Both prescription Prilosec and Prilosec OTC contain the same active ingredient, omeprazole, which effectively stops acid production. Prescription Prilosec treats diseases that require diagnosis and supervision by a doctor. Prilosec OTC treats only symptoms of frequent heartburn.

A: Prilosec OTC starts to work on the very first day of treatment, but may take 1 to 4 days for full effect (although some people get complete relief within 24 hours). Taking Prilosec OTC every day for 14 days helps to ensure that acid production is consistently controlled.

Prilosec (omeprazole) reduces the production of stomach acid by works by irreversibly blocking the actions of an enzyme responsible for acid production, called H+/K+ ATPase (also known as the gastric proton pump). The proton pump is located in the parietal cells of the stomach wall.

The FDA approved Prilosec OTC in 2003 to treat frequent heartburn safely and effectively. This is heartburn that happens two or more days a week. People should not use Prilosec OTC to treat less frequent heartburn.

Omeprazole was first made in 1979 by Swedish AB Hässle, part of Astra AB. It was the first of the proton pump inhibitors (PPI). Astra AB, now AstraZeneca, launched it as an ulcer medicine under the name Losec in Sweden.

It relieves symptoms such as heartburn, difficulty swallowing, and cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).

It relieves symptoms such as heartburn, difficulty swallowing, and cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus.

The FDA warns about overusing Prilosec OTC. It says people should not take over-the-counter PPIs for more than 14 days. The FDA also warns against taking more than three 14 day courses in a year. Overuse may lead to serious Prilosec side effects.

Taking Prilosec OTC every day for 14 days helps to ensure that acid production is consistently controlled. * When used as directed for 14 days for treating frequent heartburn. Not for immediate relief.

It relieves symptoms such as heartburn, difficulty swallowing, and cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).

If you take omeprazole for too long, there can be a risk of having long-term side effects. Taking omeprazole for a long time has been linked to: Lower bone density (weakened bones) Respiratory infections like pneumonia.