Less common side effects include, erythema, pruritus, sunburn and acne flares, which occur in fewer than 1% of people who use Differin® Gel.

This medication is used to treat acne. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Adapalene belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.

Initially, you should use the medicine every other night for the first two or three weeks. If you are tolerating the medicine OK then move up to every night. If you are getting too much irritation, then use it every 3rd night. Your goal is to eventually work up to using Differin every night.

It's believed that this purging period actually results from existing clogged pores coming to the surface, giving the inaccurate impression that things have got worse. If you keep applying Differin as recommended, you should see improvement once the purging period has concluded (usually after 6-8 weeks at the latest).

If you are getting too much irritation, then use it every 3rd night. Your goal is to eventually work up to using Differin every night. Most people get used to the Differin by the 4th to 6th week of use. all temporary and your skin will get used to the Differin and the acne will slowly improve.

Differin® Gel should be used only once daily and integrated as an important step into your morning or evening skincare routine. Try to apply the product at the same time each day.

To help clear up your acne completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a short time. If you stop using this medicine too soon, your acne may return or get worse.

That's why we always recommend using Differin for at least 12 weeks to see the full effect. And if you're wondering if it's worth sticking with it for that long, just know that in a clinical study, patients reported up to an 87% decrease in acne after 12 weeks of use.

May make acne worse: Some users report an increase in acne when starting out with Differin Gel. May also cause dry skin: Other users find that their skin became dry with regular use.

Whether you get Differin as a gel or a cream, it should be applied to the affected area daily as long as you continue to suffer from acne. If your acne completely clears up, you can stop the treatment, but be aware that your acne may return at some point.

Absolutely not. It's a common, temporary reaction that will usually subside after about 4 weeks of use. Use of Differin® Gel should not be discontinued, but be sure to always use it just once daily. Try a gentle, non-comedogenic moisturizer, like Differin Soothing Moisturizer, to help manage irritation.

It's believed that this purging period actually results from existing clogged pores coming to the surface, giving the inaccurate impression that things have got worse. If you keep applying Differin as recommended, you should see improvement once the purging period has concluded (usually after 6-8 weeks at the latest).