Greg Fraley Answer: Why, sure! That's Greg Fraley, shown in the ad playing basketball at the Fraley home near the Den at Fox Creek Golf Course on Bloomington's southwest side, on the porch with his wife, Wanda, and also teaching in a classroom at Normal U High, where he occasionally substitute teaches.

Prevagen, developed by an ingredient originally discovered in jellyfish, claims to improve short term memory. “Healthier Brain. Better Life.”

In an extensive nationwide advertising campaign, the makers of Prevagen claim that the supplement is “clinically shown to improve memory.” But, the FTC and New York allege that the company's own study found that Prevagen was no more effective than a placebo at improving memory.

For the fifth year in a row, thousands of pharmacists surveyed by the Pharmacy Times named it the top-recommended supplement for memory support in 2023. Specifically, 48% of the providers said they recommended Prevagen most often; the second-most recommended memory supplement received only 15% of their votes.

The makers of Prevagen are “deceiving millions of aging Americans” with claims that the supplement can treat age-related memory loss, AARP says in a new brief supporting a federal false advertising lawsuit.

Adverse effects of apoaequorin are very rare, but research suggests they can include headache, nausea, constipation, edema and hypertension. Prevagen comes in three formulations - regular strength, extra strength and professional strength - and 30-capsule and 60-capsule quantities.

Cholinesterase inhibitors are the first choice of treatment for memory loss. The doctor may also prescribe the single-dose drug combination Namzeric to treat moderate to severe memory loss.

Three cholinesterase inhibitors are commonly prescribed:

• Donepezil (Aricept) is approved to treat all stages of the disease. It's taken once a day as a pill.
• Galantamine (Razadyne) is approved to treat mild to moderate Alzheimer's.
• Rivastigmine (Exelon) is approved for mild to moderate Alzheimer's disease.

There are currently five medications that are FDA-approved to treat memory loss caused by Alzheimer's disease:

• Donepezil (Aricept)
• Memantine (Namenda)
• Namzaric.
• Rivastigmine (Exelon)
• Galantamine (Razadyne)

Certain vitamins and fatty acids have been said to slow or prevent memory loss. The long list of potential solutions includes vitamins like vitamin B12, herbal supplements such as ginkgo biloba, and omega-3 fatty acids.

Donanemab is currently in the headlines as a drug that appears to slow down memory and thinking decline in people living with early-stage Alzheimer's disease.

Do over-the-counter supplements help improve memory loss? Basically, no. None of the supplements marketed as being helpful for memory, or helpful in reducing dementia or reducing risk of Alzheimer's disease, has been shown to be effective.