Unisom® SleepGels®, SleepMinis®, and SleepMelts® all contain diphenhydramine, while Unisom® SleepTabs® contains a different antihistamine, doxylamine succinate. Like SleepGels®, Minis®, and Melts®, Unisom® PM contains diphenhydramine, but it also contains 200mg of acetaminophen to address minor pain while you sleep.

Unisom® is an effective and trusted sleep aid indicated for the relief of occasional sleeplessness due to fatigue or overwork. Unisom® helps to reduce difficulty falling asleep.

Doxylamine (Unisom SleepTabs) is an antihistamine, which is in many other over-the-counter products. Taking more than one medication containing an antihistamine can lead to serious side effects, such as blurry vision, reddening of skin, and confusion.

Unisom Simple Slumbers® are drug-free, and contain 5mg of melatonin, plus passionflower, lemon balm, and Vitamin B6. All Unisom® products help you get to sleep faster.

In summary, Unisom is a brand of sleep aids that can be effective at helping people fall asleep and stay asleep. It is available in several forms and is usually taken by mouth just before bedtime. While it can be helpful in the short term, it is not a long-term solution for insomnia and can have potential side effects.

Drowsiness, dizziness, constipation, stomach upset, blurred vision, or dry mouth/nose/throat may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Side effects that you should report to your care team as soon as possible: Allergic reactions - skin rash, itching, hives, swelling of the face, lips, tongue, or throat. Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss. Trouble passing urine.

Drowsiness, dizziness, headache, constipation, stomach upset, blurred vision, decreased coordination, or dry mouth/nose/throat may occur. If any of these effects last or get worse, contact your doctor or pharmacist promptly.

Melatonin is likely the safest OTC sleep aid. Excess melatonin is quickly cleared from the body and does not accumulate. Side effects are rare but may include headache, nausea, and vivid dreams.

Unisom Sleep Gels is only for short-term use until your symptoms clear up. Taking too much Unisom Sleep Gels can lead to serious heart problems, seizures, coma, or death.

Taking too much Unisom Sleep Gels can lead to serious heart problems, seizures, coma, or death.

Can I Take Unisom Products Every Night? Our medicinal sleep-aids and drug-free supplement are non-habit-forming and safe when used as directed. All Unisom products are designed to be taken only as directed for relief of occasional sleeplessness.