What kind of company is Tecfidera?

About Tecfidera

Tecfidera is a prescription medication used to treat people with relapsing forms of multiple sclerosis (MS), a chronic disease of the central nervous system. It is manufactured by Biogen, a global biotechnology company based in Cambridge, Massachusetts.

How Tecfidera Works

Tecfidera works by reducing inflammation in the brain and spinal cord, which can help to slow the progression of MS. It contains dimethyl fumarate, a small-molecule compound that is thought to activate the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway, which regulates the production of antioxidants and anti-inflammatory molecules.

Dosage and Administration

Tecfidera is available in two strengths: 120 mg and 240 mg delayed-release capsules. The recommended starting dose for adults is 120 mg twice daily for the first seven days, followed by an increase to the maintenance dose of 240 mg twice daily. It should be taken with food to reduce the risk of side effects, which can include flushing and gastrointestinal symptoms.

Efficacy and Safety

Tecfidera has been shown to significantly reduce the frequency of MS relapses and slow the progression of disability in clinical studies. It has also demonstrated a favorable safety profile, with the most common side effects being flushing, gastrointestinal symptoms, and decreases in white blood cell counts.

Availability

Tecfidera is available by prescription only and must be obtained through a healthcare provider. It is approved for use in the United States, European Union, Canada, Switzerland, Australia, and several other countries.

Conclusion

Tecfidera is a prescription medication that is used to treat people with relapsing forms of multiple sclerosis. It works by reducing inflammation in the brain and spinal cord and has been shown to significantly reduce the frequency of MS relapses and slow the progression of disability. While it may cause some side effects, it has a favorable safety profile and is available by prescription only.